1mg7: Difference between revisions

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[[Image:1mg7.png|left|200px]]


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==Crystal Structure of xol-1==
The line below this paragraph, containing "STRUCTURE_1mg7", creates the "Structure Box" on the page.
<StructureSection load='1mg7' size='340' side='right'caption='[[1mg7]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mg7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MG7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mg7 OCA], [https://pdbe.org/1mg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1mg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mg7 ProSAT]</span></td></tr>
{{STRUCTURE_1mg7|  PDB=1mg7  |  SCENE=  }}
</table>
 
== Function ==
===Crystal Structure of xol-1===
[https://www.uniprot.org/uniprot/XOL1_CAEEL XOL1_CAEEL] Acts as a primary sex-determining factor that promotes sexual differentiation. Absolutely required for proper sexual differentiation and male viability. High expression during gastrulation triggers male development, while low expression at that time triggers hermaphrodite development. Although related to GHMP kinase, its mode of action remains unclear.<ref>PMID:7813020</ref> <ref>PMID:3167975</ref>
 
== References ==
 
<references/>
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{{ABSTRACT_PUBMED_12672694}}
 
==About this Structure==
1MG7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MG7 OCA].  
 
==Reference==
XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators., Luz JG, Hassig CA, Pickle C, Godzik A, Meyer BJ, Wilson IA, Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12672694 12672694]
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Godzik, A.]]
[[Category: Godzik A]]
[[Category: Hassig, C A.]]
[[Category: Hassig CA]]
[[Category: Luz, J G.]]
[[Category: Luz JG]]
[[Category: Meyer, B J.]]
[[Category: Meyer BJ]]
[[Category: Wilson, I A.]]
[[Category: Wilson IA]]
[[Category: Alpha-beta]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  2 23:54:36 2008''