1mi6: Difference between revisions

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{{Seed}}
[[Image:1mi6.png|left|200px]]


<!--
==Docking of the modified RF2 X-ray structure into the Low Resolution Cryo-EM map of RF2 E.coli 70S Ribosome==
The line below this paragraph, containing "STRUCTURE_1mi6", creates the "Structure Box" on the page.
<SX load='1mi6' size='340' side='right' viewer='molstar' caption='[[1mi6]], [[Resolution|resolution]] 10.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mi6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MI6 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 10.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mi6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mi6 OCA], [https://pdbe.org/1mi6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mi6 RCSB], [https://www.ebi.ac.uk/pdbsum/1mi6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mi6 ProSAT]</span></td></tr>
{{STRUCTURE_1mi6|  PDB=1mi6  |  SCENE=  }}
</table>
 
== Function ==
===Docking of the modified RF2 X-ray structure into the Low Resolution Cryo-EM map of RF2 E.coli 70S Ribosome===
[https://www.uniprot.org/uniprot/RF2_ECOLI RF2_ECOLI] Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.[HAMAP-Rule:MF_00094]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_12511960}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 12511960 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mi6_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_12511960}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mi6 ConSurf].
1MI6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MI6 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</SX>
A cryo-electron microscopic study of ribosome-bound termination factor RF2., Rawat UB, Zavialov AV, Sengupta J, Valle M, Grassucci RA, Linde J, Vestergaard B, Ehrenberg M, Frank J, Nature. 2003 Jan 2;421(6918):87-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12511960 12511960]
[[Category: Escherichia coli K-12]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Ehrenberg M]]
[[Category: Ehrenberg, M]]
[[Category: Frank J]]
[[Category: Frank, J.]]
[[Category: Grassucci RA]]
[[Category: Grassucci, R A.]]
[[Category: Linde J]]
[[Category: Linde, J.]]
[[Category: Rawat UBS]]
[[Category: Rawat, U B.S.]]
[[Category: Sengupta J]]
[[Category: Sengupta, J.]]
[[Category: Valle M]]
[[Category: Valle, M.]]
[[Category: Vestergaard B]]
[[Category: Vestergaard, B.]]
[[Category: Zavialov AV]]
[[Category: Zavialov, A V.]]
[[Category: Conformational change]]
[[Category: Rf2,release complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 00:01:40 2008''

Latest revision as of 07:44, 14 February 2024

Docking of the modified RF2 X-ray structure into the Low Resolution Cryo-EM map of RF2 E.coli 70S Ribosome

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