1mk1: Difference between revisions

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{{Seed}}
[[Image:1mk1.png|left|200px]]


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==Structure of the MT-ADPRase in complex with ADPR, a Nudix enzyme==
The line below this paragraph, containing "STRUCTURE_1mk1", creates the "Structure Box" on the page.
<StructureSection load='1mk1' size='340' side='right'caption='[[1mk1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mk1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MK1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MK1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APR:ADENOSINE-5-DIPHOSPHORIBOSE'>APR</scene></td></tr>
{{STRUCTURE_1mk1|  PDB=1mk1 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mk1 OCA], [https://pdbe.org/1mk1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mk1 RCSB], [https://www.ebi.ac.uk/pdbsum/1mk1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mk1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/O33199_MYCTO O33199_MYCTO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/1mk1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mk1 ConSurf].
<div style="clear:both"></div>


===Structure of the MT-ADPRase in complex with ADPR, a Nudix enzyme===
==See Also==
 
*[[ADP-ribose pyrophosphatase 3D structures|ADP-ribose pyrophosphatase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12906832}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 12906832 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_12906832}}
 
==About this Structure==
1MK1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MK1 OCA].
 
==Reference==
Structure and mechanism of MT-ADPRase, a nudix hydrolase from Mycobacterium tuberculosis., Kang LW, Gabelli SB, Cunningham JE, O'Handley SF, Amzel LM, Structure. 2003 Aug;11(8):1015-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12906832 12906832]
[[Category: ADP-ribose diphosphatase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Amzel LM]]
[[Category: Amzel, L M.]]
[[Category: Bianchet MA]]
[[Category: Bianchet, M A.]]
[[Category: Cunningham JE]]
[[Category: Cunningham, J E.]]
[[Category: Gabelli SB]]
[[Category: Gabelli, S B.]]
[[Category: Kang L-W]]
[[Category: Handley, S F.O.]]
[[Category: O'Handley SF]]
[[Category: Kang, L W.]]
[[Category: Adenosine diphospho-ribose]]
[[Category: Adpr pyrophosphatase]]
[[Category: Adprase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Nudix hydrolase]]
[[Category: Rv1700]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 00:09:09 2008''
Retrieved from "https://proteopedia.org/1mk1"