3coq: Difference between revisions

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{{Seed}}
[[Image:3coq.jpg|left|200px]]


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==Structural Basis for Dimerization in DNA Recognition by Gal4==
The line below this paragraph, containing "STRUCTURE_3coq", creates the "Structure Box" on the page.
<StructureSection load='3coq' size='340' side='right'caption='[[3coq]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3coq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3COQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3coq| PDB=3coq |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3coq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3coq OCA], [https://pdbe.org/3coq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3coq RCSB], [https://www.ebi.ac.uk/pdbsum/3coq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3coq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GAL4_YEAST GAL4_YEAST] This protein is a positive regulator for the gene expression of the galactose-induced genes such as GAL1, GAL2, GAL7, GAL10, and MEL1 which code for the enzymes used to convert galactose to glucose. It recognizes a 17 base pair sequence in (5'-CGGRNNRCYNYNCNCCG-3') the upstream activating sequence (UAS-G) of these genes.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/3coq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3coq ConSurf].
<div style="clear:both"></div>


===Structural Basis for Dimerization in DNA Recognition by Gal4===
==See Also==
 
*[[Gal3-Gal80-Gal4|Gal3-Gal80-Gal4]]
 
__TOC__
==About this Structure==
</StructureSection>
3COQ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COQ OCA].
[[Category: Large Structures]]
[[Category: Protein complex]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Fitzgerald, M X.]]
[[Category: Synthetic construct]]
[[Category: Harper, S.]]
[[Category: Fitzgerald MX]]
[[Category: Hong, M.]]
[[Category: Harper S]]
[[Category: Luo, C.]]
[[Category: Hong M]]
[[Category: Speicher, D W.]]
[[Category: Luo C]]
[[Category: Activator]]
[[Category: Speicher DW]]
[[Category: Carbohydrate metabolism]]
[[Category: Dna-binding]]
[[Category: Galactose metabolism]]
[[Category: Helix bundle]]
[[Category: Metal-binding]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Protein-dna complex]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription/dna complex]]
[[Category: Zinc binuclear cluster]]
 
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