3tli: Difference between revisions

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{{Seed}}
[[Image:3tli.png|left|200px]]


<!--
==THERMOLYSIN (10% ISOPROPANOL SOAKED CRYSTALS)==
The line below this paragraph, containing "STRUCTURE_3tli", creates the "Structure Box" on the page.
<StructureSection load='3tli' size='340' side='right'caption='[[3tli]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3tli]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3tli|  PDB=3tli |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tli OCA], [https://pdbe.org/3tli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tli RCSB], [https://www.ebi.ac.uk/pdbsum/3tli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tli ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tl/3tli_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3tli ConSurf].
<div style="clear:both"></div>


===THERMOLYSIN (10% ISOPROPANOL SOAKED CRYSTALS)===
==See Also==
 
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_10651278}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 10651278 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_10651278}}
 
==About this Structure==
3TLI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLI OCA].
 
==Reference==
Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol., English AC, Done SH, Caves LS, Groom CR, Hubbard RE, Proteins. 1999 Dec 1;37(4):628-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10651278 10651278]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Thermolysin]]
[[Category: Done SH]]
[[Category: Done, S H.]]
[[Category: English AC]]
[[Category: English, A C.]]
[[Category: Groom CR]]
[[Category: Groom, C R.]]
[[Category: Hubbard RE]]
[[Category: Hubbard, R E.]]
[[Category: Hydrolase]]
[[Category: Metalloproteinase]]
[[Category: Organic solvent]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 13:09:29 2008''
Retrieved from "https://proteopedia.org/3tli"