4tnc: Difference between revisions

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{{Seed}}
[[Image:4tnc.png|left|200px]]


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==REFINED STRUCTURE OF CHICKEN SKELETAL MUSCLE TROPONIN C IN THE TWO-CALCIUM STATE AT 2-ANGSTROMS RESOLUTION==
The line below this paragraph, containing "STRUCTURE_4tnc", creates the "Structure Box" on the page.
<StructureSection load='4tnc' size='340' side='right'caption='[[4tnc]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4tnc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3tnc 3tnc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TNC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_4tnc| PDB=4tnc |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tnc OCA], [https://pdbe.org/4tnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tnc RCSB], [https://www.ebi.ac.uk/pdbsum/4tnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tnc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TNNC2_CHICK TNNC2_CHICK] Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tn/4tnc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4tnc ConSurf].
<div style="clear:both"></div>


===REFINED STRUCTURE OF CHICKEN SKELETAL MUSCLE TROPONIN C IN THE TWO-CALCIUM STATE AT 2-ANGSTROMS RESOLUTION===
==See Also==
 
*[[Troponin 3D structures|Troponin 3D structures]]
 
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 3338985 is the PubMed ID number.
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{{ABSTRACT_PUBMED_3338985}}
 
==About this Structure==
4TNC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3tnc 3tnc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TNC OCA].
 
==Reference==
Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-A resolution., Satyshur KA, Rao ST, Pyzalska D, Drendel W, Greaser M, Sundaralingam M, J Biol Chem. 1988 Feb 5;263(4):1628-47. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/3338985 3338985]
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Sundaralingam, M.]]
[[Category: Sundaralingam M]]
[[Category: Contractile system protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul  3 13:52:51 2008''
Retrieved from "https://proteopedia.org/4tnc"