3dl2: Difference between revisions

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New page: '''Unreleased structure''' The entry 3dl2 is ON HOLD Authors: Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Bountra, C., Wolkstrom, M., Arrow...
 
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'''Unreleased structure'''


The entry 3dl2 is ON HOLD
==Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A==
 
<StructureSection load='3dl2' size='340' side='right'caption='[[3dl2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
Authors: Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Bountra, C., Wolkstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3dl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DL2 FirstGlance]. <br>
Description: Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Jul 11 13:08:30 2008''
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dl2 OCA], [https://pdbe.org/3dl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dl2 RCSB], [https://www.ebi.ac.uk/pdbsum/3dl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dl2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UEVLD_HUMAN UEVLD_HUMAN] Possible negative regulator of polyubiquitination.<ref>PMID:12427560</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dl/3dl2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dl2 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Avvakumov GV]]
[[Category: Bochkarev A]]
[[Category: Bountra C]]
[[Category: Butler-Cole C]]
[[Category: Dhe-Paganon S]]
[[Category: Edwards AM]]
[[Category: Finerty Jr PJ]]
[[Category: Newman EM]]
[[Category: Walker JR]]
[[Category: Wolkstrom M]]
[[Category: Xue S]]