3c7m: Difference between revisions

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{{Seed}}
[[Image:3c7m.jpg|left|200px]]


<!--
==Crystal structure of reduced DsbL==
The line below this paragraph, containing "STRUCTURE_3c7m", creates the "Structure Box" on the page.
<StructureSection load='3c7m' size='340' side='right'caption='[[3c7m]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3c7m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_CFT073 Escherichia coli CFT073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C7M FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
{{STRUCTURE_3c7m| PDB=3c7m |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c7m OCA], [https://pdbe.org/3c7m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c7m RCSB], [https://www.ebi.ac.uk/pdbsum/3c7m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c7m ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DSBL_ECOL6 DSBL_ECOL6] Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT.<ref>PMID:18565543</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/3c7m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c7m ConSurf].
<div style="clear:both"></div>


===Crystal structure of reduced DsbL===
==See Also==
 
*[[Thiol:disulfide interchange protein 3D structures|Thiol:disulfide interchange protein 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_18565543}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 18565543 is the PubMed ID number.
</StructureSection>
-->
[[Category: Escherichia coli CFT073]]
{{ABSTRACT_PUBMED_18565543}}
[[Category: Large Structures]]
 
[[Category: Capitani G]]
==About this Structure==
[[Category: Glockshuber R]]
3C7M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7M OCA].
[[Category: Grimshaw JPA]]
 
[[Category: Grutter MG]]
==Reference==
[[Category: Stirnimann CU]]
DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli., Grimshaw JP, Stirnimann CU, Brozzo MS, Malojcic G, Grutter MG, Capitani G, Glockshuber R, J Mol Biol. 2008 Jul 18;380(4):667-80. Epub 2008 May 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18565543 18565543]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Capitani, G.]]
[[Category: Glockshuber, R.]]
[[Category: Grimshaw, J P.A.]]
[[Category: Grutter, M G.]]
[[Category: Stirnimann, C U.]]
[[Category: Oxidoreductase]]
[[Category: Periplasm]]
[[Category: Redox protein]]
[[Category: Redox-active center]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 16 09:19:00 2008''

Latest revision as of 09:33, 21 February 2024

Crystal structure of reduced DsbL

3c7m, resolution 1.55Å

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