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| {{Seed}}
| | #REDIRECT [[3nyl]] This PDB entry is obsolete and replaced by 3nyl |
| [[Image:1rw6.png|left|200px]] | |
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| {{STRUCTURE_1rw6| PDB=1rw6 | SCENE= }}
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| ===human APP core domain===
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| {{ABSTRACT_PUBMED_15304215}}
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| ==Disease==
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| Known disease associated with this structure: Alzheimer disease-1, APP-related OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]], Amyloidosis, cerebroarterial, Dutch type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]], Amyloidosis, cerebroarterial, Iowa type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]]
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| ==About this Structure==
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| 1RW6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Additional information on 1RW6 is available in a page on [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb79_1.html Amyloid-beta Precursor Protein] at the RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW6 OCA].
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| ==Reference==
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| The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain., Wang Y, Ha Y, Mol Cell. 2004 Aug 13;15(3):343-53. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15304215 15304215]
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| [[Category: Amyloid-beta Precursor Protein]]
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| [[Category: Homo sapiens]]
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| [[Category: Single protein]]
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| [[Category: Ha, Y.]]
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| [[Category: Wang, Y.]]
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| [[Category: Coiled-coil]]
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| [[Category: Dimer]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 10:51:51 2008''
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