1jex: Difference between revisions
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New page: left|200px<br /><applet load="1jex" size="450" color="white" frame="true" align="right" spinBox="true" caption="1jex" /> '''SOLUTION STRUCTURE OF A67V MUTANT OF RAT FER... |
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== | ==SOLUTION STRUCTURE OF A67V MUTANT OF RAT FERRO CYTOCHROME B5== | ||
<StructureSection load='1jex' size='340' side='right'caption='[[1jex]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1jex]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JEX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, models</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jex OCA], [https://pdbe.org/1jex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jex RCSB], [https://www.ebi.ac.uk/pdbsum/1jex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jex ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CYB5_RAT CYB5_RAT] Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. It is also involved in several steps of the sterol biosynthesis pathway, particularly in the C-6 double bond introduction during the C-6 desaturation. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/1jex_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jex ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Cytochrome b5 3D structures|Cytochrome b5 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Blankman JI]] | |||
[[Category: Blankman | [[Category: Dangi B]] | ||
[[Category: Dangi | [[Category: Guiles RD]] | ||
[[Category: Guiles | [[Category: Shahzad N]] | ||
[[Category: Shahzad | |||
Latest revision as of 06:17, 13 August 2026
SOLUTION STRUCTURE OF A67V MUTANT OF RAT FERRO CYTOCHROME B5
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