2zp6: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
 
(10 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:2zp6.jpg|left|200px]]


<!--
==Crystal structure of Bovine Insulin (Hexameric form)==
The line below this paragraph, containing "STRUCTURE_2zp6", creates the "Structure Box" on the page.
<StructureSection load='2zp6' size='340' side='right'caption='[[2zp6]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2zp6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZP6 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2zp6| PDB=2zp6 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zp6 OCA], [https://pdbe.org/2zp6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zp6 RCSB], [https://www.ebi.ac.uk/pdbsum/2zp6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zp6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/INS_BOVIN INS_BOVIN] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zp/2zp6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zp6 ConSurf].
<div style="clear:both"></div>


===Crystal structure of Bovine Insulin (Hexameric form)===
==See Also==
 
*[[Insulin 3D Structures|Insulin 3D Structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_16239724}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16239724 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_16239724}}
 
==About this Structure==
2ZP6 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZP6 OCA].
 
==Reference==
The structure of T6 bovine insulin., Smith GD, Pangborn WA, Blessing RH, Acta Crystallogr D Biol Crystallogr. 2005 Nov;61(Pt 11):1476-82. Epub 2005, Oct 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16239724 16239724]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Jaimohan, S M.]]
[[Category: Jaimohan SM]]
[[Category: Mandal, A B.]]
[[Category: Mandal AB]]
[[Category: Naresh, M D.]]
[[Category: Naresh MD]]
[[Category: Carbohydrate metabolism]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Glucose metabolism]]
[[Category: Hexameric form]]
[[Category: Hormone]]
[[Category: Secreted]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 11:45:21 2008''
Retrieved from "https://proteopedia.org/2zp6"