2ziu: Difference between revisions

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{{Seed}}
[[Image:2ziu.png|left|200px]]


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==Crystal structure of the Mus81-Eme1 complex==
The line below this paragraph, containing "STRUCTURE_2ziu", creates the "Structure Box" on the page.
<StructureSection load='2ziu' size='340' side='right'caption='[[2ziu]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ziu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZIU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ziu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ziu OCA], [https://pdbe.org/2ziu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ziu RCSB], [https://www.ebi.ac.uk/pdbsum/2ziu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ziu ProSAT]</span></td></tr>
{{STRUCTURE_2ziu| PDB=2ziu |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/MUS81_DANRE MUS81_DANRE] Interacts with eme1 and eme2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zi/2ziu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ziu ConSurf].
<div style="clear:both"></div>


===Crystal structure of the Mus81-Eme1 complex===
==See Also==
 
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
 
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 18413719 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18413719}}
 
==About this Structure==
2ZIU is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIU OCA].
 
==Reference==
Crystal structure of the Mus81-Eme1 complex., Chang JH, Kim JJ, Choi JM, Lee JH, Cho Y, Genes Dev. 2008 Apr 15;22(8):1093-106. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18413719 18413719]
[[Category: Danio rerio]]
[[Category: Danio rerio]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Chang, J H.]]
[[Category: Chang JH]]
[[Category: Cho, Y.]]
[[Category: Cho Y]]
[[Category: Choi, J M.]]
[[Category: Choi JM]]
[[Category: Kim, J J.]]
[[Category: Kim JJ]]
[[Category: Lee, J H.]]
[[Category: Lee JH]]
[[Category: Alternative splicing]]
[[Category: Dna damage]]
[[Category: Dna recombination]]
[[Category: Dna repair]]
[[Category: Endonuclease]]
[[Category: Helix-hairpin-helix]]
[[Category: Hydrolase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Nuclease]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:37:29 2008''
Retrieved from "https://proteopedia.org/2ziu"