1xny: Difference between revisions

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{{Seed}}
[[Image:1xny.png|left|200px]]


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==Biotin and propionyl-CoA bound to Acyl-CoA Carboxylase Beta Subunit from S. coelicolor (PccB)==
The line below this paragraph, containing "STRUCTURE_1xny", creates the "Structure Box" on the page.
<StructureSection load='1xny' size='340' side='right'caption='[[1xny]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1xny]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XNY FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1VU:PROPIONYL+COENZYME+A'>1VU</scene>, <scene name='pdbligand=BTN:BIOTIN'>BTN</scene></td></tr>
{{STRUCTURE_1xny|  PDB=1xny  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xny OCA], [https://pdbe.org/1xny PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xny RCSB], [https://www.ebi.ac.uk/pdbsum/1xny PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xny ProSAT]</span></td></tr>
 
</table>
===Biotin and propionyl-CoA bound to Acyl-CoA Carboxylase Beta Subunit from S. coelicolor (PccB)===
== Function ==
 
[https://www.uniprot.org/uniprot/Q9X4K7_STRCH Q9X4K7_STRCH]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15518551}}, adds the Publication Abstract to the page
Check<jmol>
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  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xn/1xny_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15518551}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1XNY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNY OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xny ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Crystal structure of the beta-subunit of acyl-CoA carboxylase: structure-based engineering of substrate specificity., Diacovich L, Mitchell DL, Pham H, Gago G, Melgar MM, Khosla C, Gramajo H, Tsai SC, Biochemistry. 2004 Nov 9;43(44):14027-36. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15518551 15518551]
</StructureSection>
[[Category: Propionyl-CoA carboxylase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
[[Category: Diacovich, L.]]
[[Category: Diacovich L]]
[[Category: Gago, G.]]
[[Category: Gago G]]
[[Category: Gramajo, H.]]
[[Category: Gramajo H]]
[[Category: Khosla, C.]]
[[Category: Khosla C]]
[[Category: Melgar, M M.]]
[[Category: Melgar MM]]
[[Category: Mitchell, D L.]]
[[Category: Mitchell DL]]
[[Category: Pham, H.]]
[[Category: Pham H]]
[[Category: Tsai, S C.]]
[[Category: Tsai S-C]]
[[Category: Acyl-coa carboxylase]]
[[Category: Carboxyltransferase]]
[[Category: Polyketide]]
[[Category: Polyketide synthase]]
 
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