1r4w: Difference between revisions

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{{Seed}}
[[Image:1r4w.png|left|200px]]


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==Crystal structure of Mitochondrial class kappa glutathione transferase==
The line below this paragraph, containing "STRUCTURE_1r4w", creates the "Structure Box" on the page.
<StructureSection load='1r4w' size='340' side='right'caption='[[1r4w]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1r4w]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R4W FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr>
{{STRUCTURE_1r4w|  PDB=1r4w |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r4w OCA], [https://pdbe.org/1r4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r4w RCSB], [https://www.ebi.ac.uk/pdbsum/1r4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r4w ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSTK1_RAT GSTK1_RAT] Might confer protection against genotoxic and cytotoxic electrophiles in the mitochondrial compartment.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r4/1r4w_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r4w ConSurf].
<div style="clear:both"></div>


===Crystal structure of Mitochondrial class kappa glutathione transferase===
==See Also==
 
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_14717589}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 14717589 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_14717589}}
 
==About this Structure==
1R4W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R4W OCA].
 
==Reference==
Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochondrial class kappa enzyme rGSTK1-1., Ladner JE, Parsons JF, Rife CL, Gilliland GL, Armstrong RN, Biochemistry. 2004 Jan 20;43(2):352-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14717589 14717589]
[[Category: Glutathione transferase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Armstrong RN]]
[[Category: Armstrong, R N.]]
[[Category: Gilliland GL]]
[[Category: Gilliland, G L.]]
[[Category: Ladner JE]]
[[Category: Ladner, J E.]]
[[Category: Parsons JF]]
[[Category: Parsons, J F.]]
[[Category: Rife CL]]
[[Category: Rife, C L.]]
[[Category: Glutathione transferase]]
[[Category: Glutathione-s-transferase]]
[[Category: Kappa gst]]
[[Category: Rgstk1-1]]
 
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Retrieved from "https://proteopedia.org/1r4w"