2au6: Difference between revisions

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{{Seed}}
[[Image:2au6.png|left|200px]]


<!--
==Crystal structure of catalytic intermediate of inorganic pyrophosphatase==
The line below this paragraph, containing "STRUCTURE_2au6", creates the "Structure Box" on the page.
<StructureSection load='2au6' size='340' side='right'caption='[[2au6]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2au6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AU6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AU6 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
{{STRUCTURE_2au6| PDB=2au6 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2au6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2au6 OCA], [https://pdbe.org/2au6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2au6 RCSB], [https://www.ebi.ac.uk/pdbsum/2au6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2au6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IPYR_ECOLI IPYR_ECOLI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/au/2au6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2au6 ConSurf].
<div style="clear:both"></div>


===Crystal structure of catalytic intermediate of inorganic pyrophosphatase===
==See Also==
 
*[[Inorganic pyrophosphatase 3D structures|Inorganic pyrophosphatase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_17196979}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 17196979 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_17196979}}
 
==About this Structure==
2AU6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AU6 OCA].
 
==Reference==
Reversible inhibition of Escherichia coli inorganic pyrophosphatase by fluoride: trapped catalytic intermediates in cryo-crystallographic studies., Samygina VR, Moiseev VM, Rodina EV, Vorobyeva NN, Popov AN, Kurilova SA, Nazarova TI, Avaeva SM, Bartunik HD, J Mol Biol. 2007 Mar 2;366(4):1305-17. Epub 2006 Dec 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17196979 17196979]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Inorganic diphosphatase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Avaeva SM]]
[[Category: Avaeva, S M.]]
[[Category: Bartunik HD]]
[[Category: Bartunik, H D.]]
[[Category: Popov AN]]
[[Category: Popov, A N.]]
[[Category: Samygina VR]]
[[Category: Samygina, V R.]]
[[Category: Hydrolase]]
[[Category: Inorganic pyrophosphatase]]
[[Category: Intermediate]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:37:45 2008''

Latest revision as of 13:42, 13 March 2024

Crystal structure of catalytic intermediate of inorganic pyrophosphatase

2au6, resolution 1.20Å

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