1k9z: Difference between revisions

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New page: left|200px<br /><applet load="1k9z" size="450" color="white" frame="true" align="right" spinBox="true" caption="1k9z, resolution 1.50Å" /> '''The PAPase Hal2p com...
 
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[[Image:1k9z.gif|left|200px]]<br /><applet load="1k9z" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1k9z, resolution 1.50&Aring;" />
'''The PAPase Hal2p complexed with zinc ions'''<br />


==About this Structure==
==The PAPase Hal2p complexed with zinc ions==
1K9Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with ZN and BME as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3'(2'),5'-bisphosphate_nucleotidase 3'(2'),5'-bisphosphate nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.7 3.1.3.7] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1K9Z OCA].  
<StructureSection load='1k9z' size='340' side='right'caption='[[1k9z]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
[[Category: 3'(2'),5'-bisphosphate nucleotidase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1k9z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K9Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K9Z FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k9z OCA], [https://pdbe.org/1k9z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k9z RCSB], [https://www.ebi.ac.uk/pdbsum/1k9z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k9z ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MET22_YEAST MET22_YEAST] Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Regulates the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. Involved in salt tolerance. Confers resistance to lithium.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k9/1k9z_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k9z ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Albert A]]
[[Category: Albert, A.]]
[[Category: Blundell TL]]
[[Category: Blundell, T.L.]]
[[Category: Patel S]]
[[Category: Patel, S.]]
[[Category: BME]]
[[Category: ZN]]
[[Category: inositol]]
[[Category: nucleotidase]]
[[Category: salt tolerance]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 18:59:20 2007''

Latest revision as of 08:54, 16 August 2023

The PAPase Hal2p complexed with zinc ions

1k9z, resolution 1.50Å

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