1mum: Difference between revisions

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{{Seed}}
[[Image:1mum.png|left|200px]]


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==Structure of the 2-Methylisocitrate Lyase (PrpB) from Escherichia coli==
The line below this paragraph, containing "STRUCTURE_1mum", creates the "Structure Box" on the page.
<StructureSection load='1mum' size='340' side='right'caption='[[1mum]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mum]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MUM FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_1mum|  PDB=1mum  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mum OCA], [https://pdbe.org/1mum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mum RCSB], [https://www.ebi.ac.uk/pdbsum/1mum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mum ProSAT]</span></td></tr>
 
</table>
===Structure of the 2-Methylisocitrate Lyase (PrpB) from Escherichia coli===
== Function ==
 
[https://www.uniprot.org/uniprot/PRPB_ECOLI PRPB_ECOLI] Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate.<ref>PMID:11422389</ref> <ref>PMID:15723538</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mu/1mum_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12706720}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1MUM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUM OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mum ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Crystal structure of 2-methylisocitrate lyase (PrpB) from Escherichia coli and modelling of its ligand bound active centre., Grimm C, Evers A, Brock M, Maerker C, Klebe G, Buckel W, Reuter K, J Mol Biol. 2003 May 2;328(3):609-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12706720 12706720]
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Methylisocitrate lyase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Grimm C]]
[[Category: Grimm, C.]]
[[Category: Reuter K]]
[[Category: Reuter, K.]]
[[Category: Lyase]]
[[Category: Methylcitrate cycle]]
[[Category: Methylisocitrate]]
[[Category: Prpb]]
[[Category: Tim-barrel]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:12:51 2008''
Retrieved from "https://proteopedia.org/1mum"