1on2: Difference between revisions

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{{Seed}}
[[Image:1on2.png|left|200px]]


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==Bacillus subtilis Manganese Transport Regulator (MntR), D8M Mutant, Bound to Manganese==
The line below this paragraph, containing "STRUCTURE_1on2", creates the "Structure Box" on the page.
<StructureSection load='1on2' size='340' side='right'caption='[[1on2]], [[Resolution|resolution]] 1.61&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1on2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ON2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ON2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.61&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
{{STRUCTURE_1on2|  PDB=1on2  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1on2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1on2 OCA], [https://pdbe.org/1on2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1on2 RCSB], [https://www.ebi.ac.uk/pdbsum/1on2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1on2 ProSAT]</span></td></tr>
 
</table>
===Bacillus subtilis Manganese Transport Regulator (MntR), D8M Mutant, Bound to Manganese===
== Function ==
 
[https://www.uniprot.org/uniprot/MNTR_BACSU MNTR_BACSU] Central regulator of manganese homeostasis. In the presence of manganese, it mediates repression of the manganese transporter MntH; under low manganese conditions, it activates the transcription of the mntABCD operon.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12847518}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 12847518 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/1on2_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12847518}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1ON2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ON2 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1on2 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Structure of the manganese-bound manganese transport regulator of Bacillus subtilis., Glasfeld A, Guedon E, Helmann JD, Brennan RG, Nat Struct Biol. 2003 Aug;10(8):652-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12847518 12847518]
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Brennan, R G.]]
[[Category: Brennan RG]]
[[Category: Glasfeld, A.]]
[[Category: Glasfeld A]]
[[Category: Guedon, E.]]
[[Category: Guedon E]]
[[Category: Helmann, J D.]]
[[Category: Helmann JD]]
[[Category: Dna-binding protein]]
[[Category: Helix-turn-helix]]
[[Category: Metalloregulatory protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:34:12 2008''
Retrieved from "https://proteopedia.org/1on2"