1kjo: Difference between revisions

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New page: left|200px<br /><applet load="1kjo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1kjo, resolution 1.60Å" /> '''Thermolysin complexe...
 
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[[Image:1kjo.jpg|left|200px]]<br /><applet load="1kjo" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1kjo, resolution 1.60&Aring;" />
'''Thermolysin complexed with Z-L-Threonine (benzyloxycarbonyl-L-Threonine)'''<br />


==About this Structure==
==Thermolysin complexed with Z-L-Threonine (benzyloxycarbonyl-L-Threonine)==
1KJO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] with CA, ZN, PHQ and THR as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1KJO OCA].  
<StructureSection load='1kjo' size='340' side='right'caption='[[1kjo]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1kjo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KJO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KJO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene>, <scene name='pdbligand=THR:THREONINE'>THR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kjo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kjo OCA], [https://pdbe.org/1kjo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kjo RCSB], [https://www.ebi.ac.uk/pdbsum/1kjo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kjo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kj/1kjo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kjo ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
__TOC__
</StructureSection>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Thermolysin]]
[[Category: Kidokoro S]]
[[Category: Kidokoro, S.]]
[[Category: Senda M]]
[[Category: Senda, M.]]
[[Category: Senda T]]
[[Category: Senda, T.]]
[[Category: CA]]
[[Category: PHQ]]
[[Category: THR]]
[[Category: ZN]]
[[Category: benzyloxycarbonyl amino acid]]
[[Category: hydrolase]]
[[Category: metalloproteinase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 19:17:41 2007''