2r70: Difference between revisions

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{{Seed}}
[[Image:2r70.png|left|200px]]


<!--
==Crystal structure of infectious bursal disease virus VP1 polymerase, cocrystallized with an oligopeptide mimicking the VP3 C-terminus.==
The line below this paragraph, containing "STRUCTURE_2r70", creates the "Structure Box" on the page.
<StructureSection load='2r70' size='340' side='right'caption='[[2r70]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2r70]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Infectious_bursal_disease_virus Infectious bursal disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R70 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r70 OCA], [https://pdbe.org/2r70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r70 RCSB], [https://www.ebi.ac.uk/pdbsum/2r70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r70 ProSAT]</span></td></tr>
{{STRUCTURE_2r70|  PDB=2r70  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of infectious bursal disease virus VP1 polymerase, cocrystallized with an oligopeptide mimicking the VP3 C-terminus.===
[https://www.uniprot.org/uniprot/RDRP_IBDV RDRP_IBDV] RNA-dependent RNA polymerase which is found both free and covalently attached to the genomic RNA. May also contain guanylyl and methyl transferase activities (By similarity).
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_18077388}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 18077388 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/2r70_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_18077388}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r70 ConSurf].
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R70 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Activation mechanism of a noncanonical RNA-dependent RNA polymerase., Garriga D, Navarro A, Querol-Audi J, Abaitua F, Rodriguez JF, Verdaguer N, Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20540-5. Epub 2007 Dec 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18077388 18077388]
[[Category: Abaitua, F.]]
[[Category: Garriga, D.]]
[[Category: Navarro, A.]]
[[Category: Querol-Audi, J.]]
[[Category: Rodriguez, J F.]]
[[Category: Verdaguer, N.]]
[[Category: Activation]]
[[Category: Birnavirus]]
[[Category: Ibdv]]
[[Category: Infectious bursal disease virus]]
[[Category: Infectious bursal disease virus]]
[[Category: Polymerase]]
[[Category: Large Structures]]
[[Category: Transferase]]
[[Category: Abaitua F]]
[[Category: Vp1]]
[[Category: Garriga D]]
[[Category: Vp3]]
[[Category: Navarro A]]
 
[[Category: Querol-Audi J]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:50:12 2008''
[[Category: Rodriguez JF]]
[[Category: Verdaguer N]]

Latest revision as of 09:20, 21 February 2024

Crystal structure of infectious bursal disease virus VP1 polymerase, cocrystallized with an oligopeptide mimicking the VP3 C-terminus.

2r70, resolution 2.70Å

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