2azo: Difference between revisions

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[[Image:2azo.png|left|200px]]


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==DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI==
The line below this paragraph, containing "STRUCTURE_2azo", creates the "Structure Box" on the page.
<StructureSection load='2azo' size='340' side='right'caption='[[2azo]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2azo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AZO FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2azo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2azo OCA], [https://pdbe.org/2azo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2azo RCSB], [https://www.ebi.ac.uk/pdbsum/2azo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2azo ProSAT]</span></td></tr>
{{STRUCTURE_2azo| PDB=2azo |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/MUTH_ECOLI MUTH_ECOLI] Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.[HAMAP-Rule:MF_00759]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/az/2azo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2azo ConSurf].
<div style="clear:both"></div>


===DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI===
==See Also==
 
*[[DNA mismatch repair protein 3D structures|DNA mismatch repair protein 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_9482749}}, adds the Publication Abstract to the page
[[Category: Escherichia coli K-12]]
(as it appears on PubMed at http://www.pubmed.gov), where 9482749 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Yang W]]
{{ABSTRACT_PUBMED_9482749}}
 
==About this Structure==
2AZO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AZO OCA].
 
==Reference==
Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases., Ban C, Yang W, EMBO J. 1998 Mar 2;17(5):1526-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9482749 9482749]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Yang, W.]]
[[Category: Dna repair]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Muth]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:13:46 2008''

Latest revision as of 09:14, 14 February 2024

DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI

2azo, resolution 2.30Å

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