2i8u: Difference between revisions

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{{Seed}}
[[Image:2i8u.png|left|200px]]


<!--
==GDP-mannose mannosyl hydrolase-calcium-GDP product complex==
The line below this paragraph, containing "STRUCTURE_2i8u", creates the "Structure Box" on the page.
<StructureSection load='2i8u' size='340' side='right'caption='[[2i8u]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2i8u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I8U FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
{{STRUCTURE_2i8u|  PDB=2i8u  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i8u OCA], [https://pdbe.org/2i8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i8u RCSB], [https://www.ebi.ac.uk/pdbsum/2i8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i8u ProSAT]</span></td></tr>
 
</table>
===GDP-mannose mannosyl hydrolase-calcium-GDP product complex===
== Function ==
 
[https://www.uniprot.org/uniprot/Q6XQ58_ECOLX Q6XQ58_ECOLX] Hydrolyzes GDP-mannose.[HAMAP-Rule:MF_00941]
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_17371001}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 17371001 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/2i8u_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_17371001}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2I8U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I8U OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i8u ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Molecular basis for substrate selectivity and specificity by an LPS biosynthetic enzyme., Zou Y, Li C, Brunzelle JS, Nair SK, Biochemistry. 2007 Apr 10;46(14):4294-304. Epub 2007 Mar 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17371001 17371001]
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Brunzelle, J S.]]
[[Category: Brunzelle JS]]
[[Category: Li, C.]]
[[Category: Li C]]
[[Category: Nair, S K.]]
[[Category: Nair SK]]
[[Category: Zou, Y.]]
[[Category: Zou Y]]
[[Category: Lipopolysaccharide]]
[[Category: Nudix enzyme]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:35:27 2008''

Latest revision as of 09:02, 21 February 2024

GDP-mannose mannosyl hydrolase-calcium-GDP product complex

2i8u, resolution 1.40Å

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