1p7a: Difference between revisions

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{{Seed}}
[[Image:1p7a.png|left|200px]]


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==Solution Structure of the Third Zinc Finger from BKLF==
The line below this paragraph, containing "STRUCTURE_1p7a", creates the "Structure Box" on the page.
<StructureSection load='1p7a' size='340' side='right'caption='[[1p7a]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1p7a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P7A FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_1p7a|  PDB=1p7a  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p7a OCA], [https://pdbe.org/1p7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p7a RCSB], [https://www.ebi.ac.uk/pdbsum/1p7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p7a ProSAT]</span></td></tr>
 
</table>
===Solution Stucture of the Third Zinc Finger from BKLF===
== Function ==
 
[https://www.uniprot.org/uniprot/KLF3_MOUSE KLF3_MOUSE] Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.<ref>PMID:8657145</ref> <ref>PMID:15684403</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12736264}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 12736264 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p7/1p7a_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12736264}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1P7A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7A OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p7a ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions., Simpson RJ, Cram ED, Czolij R, Matthews JM, Crossley M, Mackay JP, J Biol Chem. 2003 Jul 25;278(30):28011-8. Epub 2003 May 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12736264 12736264]
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Cram ED]]
[[Category: Cram, E D.]]
[[Category: Crossley M]]
[[Category: Crossley, M.]]
[[Category: Czolij R]]
[[Category: Czolij, R.]]
[[Category: Mackay JP]]
[[Category: Mackay, J P.]]
[[Category: Matthews JM]]
[[Category: Matthews, J M.]]
[[Category: Simpson RJY]]
[[Category: Simpson, R J.Y.]]
[[Category: Classical zinc finger]]
[[Category: Kruppel-like]]
[[Category: Transcription factor]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:21:35 2008''
Retrieved from "https://proteopedia.org/1p7a"