3b8i: Difference between revisions

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{{Seed}}
[[Image:3b8i.png|left|200px]]


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==Crystal Structure of Oxaloacetate Decarboxylase from Pseudomonas Aeruginosa (PA4872) in complex with oxalate and Mg2+.==
The line below this paragraph, containing "STRUCTURE_3b8i", creates the "Structure Box" on the page.
<StructureSection load='3b8i' size='340' side='right'caption='[[3b8i]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3b8i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B8I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B8I FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
{{STRUCTURE_3b8i|  PDB=3b8i  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b8i OCA], [https://pdbe.org/3b8i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b8i RCSB], [https://www.ebi.ac.uk/pdbsum/3b8i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b8i ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Oxaloacetate Decarboxylase from Pseudomonas Aeruginosa (PA4872) in complex with oxalate and Mg2+.===
== Function ==
 
[https://www.uniprot.org/uniprot/OADC_PSEAE OADC_PSEAE] Catalyzes the decarboxylation of oxaloacetate into pyruvate with high efficiency. Is also able to decarboxylate 3-methyloxaloacetate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.<ref>PMID:18081320</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b8/3b8i_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_18081320}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3B8I is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B8I OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b8i ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily., Narayanan BC, Niu W, Han Y, Zou J, Mariano PS, Dunaway-Mariano D, Herzberg O, Biochemistry. 2008 Jan 8;47(1):167-82. Epub 2007 Dec 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18081320 18081320]
<references/>
[[Category: Oxaloacetate decarboxylase]]
__TOC__
[[Category: Pseudomonas aeruginosa]]
</StructureSection>
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Herzberg, O]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Narayanan, B C.]]
[[Category: Herzberg O]]
[[Category: Alpha/beta barrel]]
[[Category: Narayanan BC]]
[[Category: Helix swapping]]
[[Category: Lyase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:48:00 2008''

Latest revision as of 09:28, 21 February 2024

Crystal Structure of Oxaloacetate Decarboxylase from Pseudomonas Aeruginosa (PA4872) in complex with oxalate and Mg2+.

3b8i, resolution 1.90Å

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