3pva: Difference between revisions
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New page: left|200px<br /><applet load="3pva" size="450" color="white" frame="true" align="right" spinBox="true" caption="3pva, resolution 2.8Å" /> '''PENICILLIN V ACYLASE ... |
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== | ==PENICILLIN V ACYLASE FROM B. SPHAERICUS== | ||
<StructureSection load='3pva' size='340' side='right'caption='[[3pva]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3pva]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PVA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pva OCA], [https://pdbe.org/3pva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pva RCSB], [https://www.ebi.ac.uk/pdbsum/3pva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pva ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PAC_LYSSH PAC_LYSSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/3pva_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3pva ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
Penicillin | *[[Penicillin acylase|Penicillin acylase]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Lysinibacillus sphaericus]] | [[Category: Lysinibacillus sphaericus]] | ||
[[Category: Brannigan JA]] | |||
[[Category: Dauter Z]] | |||
[[Category: Brannigan | [[Category: Dodson EJ]] | ||
[[Category: Dauter | [[Category: Dodson GG]] | ||
[[Category: Dodson | [[Category: Mcvey CE]] | ||
[[Category: Dodson | [[Category: Pundle AV]] | ||
[[Category: Mcvey | [[Category: Rao KN]] | ||
[[Category: Pundle | [[Category: Sivaraman H]] | ||
[[Category: Rao | [[Category: Suresh CG]] | ||
[[Category: Sivaraman | [[Category: Verma CS]] | ||
[[Category: Suresh | |||
[[Category: Verma | |||
Latest revision as of 00:34, 28 December 2023
PENICILLIN V ACYLASE FROM B. SPHAERICUS
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