1u7o: Difference between revisions

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{{Seed}}
[[Image:1u7o.png|left|200px]]


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==Magnesium Dependent Phosphatase 1 (MDP-1)==
The line below this paragraph, containing "STRUCTURE_1u7o", creates the "Structure Box" on the page.
<StructureSection load='1u7o' size='340' side='right'caption='[[1u7o]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1u7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U7O FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
{{STRUCTURE_1u7o|  PDB=1u7o  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u7o OCA], [https://pdbe.org/1u7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u7o RCSB], [https://www.ebi.ac.uk/pdbsum/1u7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u7o ProSAT]</span></td></tr>
 
</table>
===Magnesium Dependent Phosphatase 1 (MDP-1)===
== Function ==
 
[https://www.uniprot.org/uniprot/MGDP1_MOUSE MGDP1_MOUSE] Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.<ref>PMID:10889041</ref> <ref>PMID:11601995</ref> <ref>PMID:15461449</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15461449}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u7/1u7o_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15461449}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1U7O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U7O OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u7o ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily., Peisach E, Selengut JD, Dunaway-Mariano D, Allen KN, Biochemistry. 2004 Oct 12;43(40):12770-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15461449 15461449]
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Allen KN]]
[[Category: Allen, K N.]]
[[Category: Dunaway-Mariano D]]
[[Category: Dunaway-Mariano, D.]]
[[Category: Peisach E]]
[[Category: Peisach, E.]]
[[Category: Selengut JD]]
[[Category: Selengut, J D.]]
[[Category: Aspartate nucleophile]]
[[Category: Class iii]]
[[Category: Enzyme evolution]]
[[Category: Had superfamily]]
[[Category: Phosphoryl transfer]]
[[Category: Phosphotyrosine phosphatase]]
[[Category: Structural enzymology]]
 
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