1yfu: Difference between revisions

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{{Seed}}
[[Image:1yfu.png|left|200px]]


<!--
==Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans==
The line below this paragraph, containing "STRUCTURE_1yfu", creates the "Structure Box" on the page.
<StructureSection load='1yfu' size='340' side='right'caption='[[1yfu]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1yfu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_metallidurans Cupriavidus metallidurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YFU FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
{{STRUCTURE_1yfu| PDB=1yfu |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yfu OCA], [https://pdbe.org/1yfu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yfu RCSB], [https://www.ebi.ac.uk/pdbsum/1yfu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yfu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/3HAO_CUPMC 3HAO_CUPMC] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[HAMAP-Rule:MF_00825]<ref>PMID:15909977</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yf/1yfu_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yfu ConSurf].
<div style="clear:both"></div>


===Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans===
==See Also==
 
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_15909978}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 15909978 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_15909978}}
 
==About this Structure==
1YFU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cupriavidus_metallidurans Cupriavidus metallidurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YFU OCA].
 
==Reference==
Structural studies on 3-hydroxyanthranilate-3,4-dioxygenase: the catalytic mechanism of a complex oxidation involved in NAD biosynthesis., Zhang Y, Colabroy KL, Begley TP, Ealick SE, Biochemistry. 2005 May 31;44(21):7632-43. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15909978 15909978]
[[Category: 3-hydroxyanthranilate 3,4-dioxygenase]]
[[Category: Cupriavidus metallidurans]]
[[Category: Cupriavidus metallidurans]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Begley, T P.]]
[[Category: Begley TP]]
[[Category: Colabroy, K L.]]
[[Category: Colabroy KL]]
[[Category: Ealick, S E.]]
[[Category: Ealick SE]]
[[Category: Zhang, Y.]]
[[Category: Zhang Y]]
[[Category: Cupin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:18:30 2008''
Retrieved from "https://proteopedia.org/1yfu"