1t7o: Difference between revisions

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{{Seed}}
[[Image:1t7o.png|left|200px]]


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==Crystal structure of the M564G mutant of murine carnitine acetyltransferase in complex with carnitine==
The line below this paragraph, containing "STRUCTURE_1t7o", creates the "Structure Box" on the page.
<StructureSection load='1t7o' size='340' side='right'caption='[[1t7o]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1t7o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T7O FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=152:CARNITINE'>152</scene></td></tr>
{{STRUCTURE_1t7o| PDB=1t7o |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t7o OCA], [https://pdbe.org/1t7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t7o RCSB], [https://www.ebi.ac.uk/pdbsum/1t7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t7o ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CACP_MOUSE CACP_MOUSE] Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t7/1t7o_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t7o ConSurf].
<div style="clear:both"></div>


===Crystal structure of the M564G mutant of murine carnitine acetyltransferase in complex with carnitine===
==See Also==
 
*[[Carnitine acetyltransferase|Carnitine acetyltransferase]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_15155726}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 15155726 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15155726}}
 
==About this Structure==
1T7O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7O OCA].
 
==Reference==
Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase., Hsiao YS, Jogl G, Tong L, J Biol Chem. 2004 Jul 23;279(30):31584-9. Epub 2004 May 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15155726 15155726]
[[Category: Carnitine O-acetyltransferase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Hsiao Y-S]]
[[Category: Hsiao, Y S.]]
[[Category: Jogl G]]
[[Category: Jogl, G.]]
[[Category: Tong L]]
[[Category: Tong, L.]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:33:50 2008''
Retrieved from "https://proteopedia.org/1t7o"