2ay0: Difference between revisions

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{{Seed}}
[[Image:2ay0.png|left|200px]]


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==Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.==
The line below this paragraph, containing "STRUCTURE_2ay0", creates the "Structure Box" on the page.
<StructureSection load='2ay0' size='340' side='right'caption='[[2ay0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ay0]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AY0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
{{STRUCTURE_2ay0| PDB=2ay0 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ay0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ay0 OCA], [https://pdbe.org/2ay0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ay0 RCSB], [https://www.ebi.ac.uk/pdbsum/2ay0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ay0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PUTA_ECOLI PUTA_ECOLI] Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ay/2ay0_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ay0 ConSurf].
<div style="clear:both"></div>


===Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.===
==See Also==
 
*[[Proline utilization A|Proline utilization A]]
 
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(as it appears on PubMed at http://www.pubmed.gov), where 17001030 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17001030}}
 
==About this Structure==
2AY0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AY0 OCA].
 
==Reference==
Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition., Larson JD, Jenkins JL, Schuermann JP, Zhou Y, Becker DF, Tanner JJ, Protein Sci. 2006 Nov;15(11):2630-41. Epub 2006 Sep 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17001030 17001030]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Becker, D F.]]
[[Category: Becker DF]]
[[Category: Jenkins, J L.]]
[[Category: Jenkins JL]]
[[Category: Larson, J D.]]
[[Category: Larson JD]]
[[Category: Schuermann, J P.]]
[[Category: Schuermann JP]]
[[Category: Tanner, J J.]]
[[Category: Tanner JJ]]
[[Category: Zhou, Y.]]
[[Category: Zhou Y]]
[[Category: Dna-binding domain]]
[[Category: Proline catabolism]]
[[Category: Proline utilization some]]
[[Category: Puta]]
[[Category: Ribbon-helix-helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:34:41 2008''
Retrieved from "https://proteopedia.org/2ay0"