1u2e: Difference between revisions

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{{Seed}}
[[Image:1u2e.png|left|200px]]


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==Crystal Structure of the C-C bond hydrolase MhpC==
The line below this paragraph, containing "STRUCTURE_1u2e", creates the "Structure Box" on the page.
<StructureSection load='1u2e' size='340' side='right'caption='[[1u2e]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1u2e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U2E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
{{STRUCTURE_1u2e|  PDB=1u2e  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2e OCA], [https://pdbe.org/1u2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u2e RCSB], [https://www.ebi.ac.uk/pdbsum/1u2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2e ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of the C-C bond hydrolase MhpC===
== Function ==
 
[https://www.uniprot.org/uniprot/MHPC_ECOLI MHPC_ECOLI] Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid. MhpC shows some selectivity for the carboxylate of the side chain.<ref>PMID:9098055</ref> <ref>PMID:9315862</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15663942}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u2/1u2e_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15663942}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1U2E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2E OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u2e ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
The structure of the C-C bond hydrolase MhpC provides insights into its catalytic mechanism., Dunn G, Montgomery MG, Mohammed F, Coker A, Cooper JB, Robertson T, Garcia JL, Bugg TD, Wood SP, J Mol Biol. 2005 Feb 11;346(1):253-65. Epub 2004 Dec 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15663942 15663942]
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bugg, T D.H.]]
[[Category: Bugg TDH]]
[[Category: Coker, A.]]
[[Category: Coker A]]
[[Category: Dunn, G.]]
[[Category: Dunn G]]
[[Category: Garcia, J L.]]
[[Category: Garcia J-L]]
[[Category: Mohammed, F.]]
[[Category: Mohammed F]]
[[Category: Montgomery, M G.]]
[[Category: Montgomery MG]]
[[Category: Robertson, T.]]
[[Category: Robertson T]]
[[Category: Wood, S P.]]
[[Category: Wood SP]]
[[Category: Alpha/beta hydrolase fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:38:32 2008''

Latest revision as of 13:30, 13 March 2024

Crystal Structure of the C-C bond hydrolase MhpC

1u2e, resolution 2.10Å

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