1rsb: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,332,843 edits
No edit summary
Tag: Manual revert
 
(10 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1rsb.png|left|200px]]


<!--
==X-ray study of the DNA oligomer d(ATATAT) in P65 space group==
The line below this paragraph, containing "STRUCTURE_1rsb", creates the "Structure Box" on the page.
<StructureSection load='1rsb' size='340' side='right'caption='[[1rsb]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1rsb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RSB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rsb OCA], [https://pdbe.org/1rsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rsb RCSB], [https://www.ebi.ac.uk/pdbsum/1rsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rsb ProSAT]</span></td></tr>
{{STRUCTURE_1rsb|  PDB=1rsb  |  SCENE=  }}
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We present and analyze the structure of the oligonucleotide d(ATATAT) found in two different forms by X-ray crystallography and in solution by NMR. We find that in both crystal lattices the oligonucleotide forms an antiparallel double helical duplex in which base pairing is of the Hoogsteen type. The double helix is apparently very similar to the standard B-form of DNA, with about 10 base pairs per turn. However, the adenines in the duplex are flipped over; as a result, the physicochemical features of both grooves of the helix are changed. In particular, the minor groove is narrow and hydrophobic. On the other hand, d(ATATAT) displays a propensity to adopt the B conformation in solution. These results confirm the polymorphism of AT-rich sequences in DNA. Furthermore, we show that extrahelical adenines and thymines can be minor groove binders in Hoogsteen DNA.


===X-ray study of the DNA oligomer d(ATATAT) in P65 space group===
X-ray and NMR studies of the DNA oligomer d(ATATAT): Hoogsteen base pairing in duplex DNA.,Abrescia NG, Gonzalez C, Gouyette C, Subirana JA Biochemistry. 2004 Apr 13;43(14):4092-100. PMID:15065851<ref>PMID:15065851</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
<!--
</div>
The line below this paragraph, {{ABSTRACT_PUBMED_15065851}}, adds the Publication Abstract to the page
<div class="pdbe-citations 1rsb" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 15065851 is the PubMed ID number.
== References ==
-->
<references/>
{{ABSTRACT_PUBMED_15065851}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RSB OCA].
[[Category: Abrescia NG]]
 
[[Category: Gonzalez C]]
==Reference==
[[Category: Gouyette C]]
X-ray and NMR studies of the DNA oligomer d(ATATAT): Hoogsteen base pairing in duplex DNA., Abrescia NG, Gonzalez C, Gouyette C, Subirana JA, Biochemistry. 2004 Apr 13;43(14):4092-100. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15065851 15065851]
[[Category: Subirana JA]]
[[Category: Abrescia, N G.]]
[[Category: Gonzalez, C.]]
[[Category: Gouyette, C.]]
[[Category: Subirana, J A.]]
[[Category: Antiparallel hoogsteen dna]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:41:30 2008''

Latest revision as of 08:07, 4 March 2026

X-ray study of the DNA oligomer d(ATATAT) in P65 space group

1rsb, resolution 2.17Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1rsb&oldid=4425994"