1otg: Difference between revisions

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{{Seed}}
[[Image:1otg.png|left|200px]]


<!--
==5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE==
The line below this paragraph, containing "STRUCTURE_1otg", creates the "Structure Box" on the page.
<StructureSection load='1otg' size='340' side='right'caption='[[1otg]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1otg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_C Escherichia coli C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OTG FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1otg|  PDB=1otg  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1otg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1otg OCA], [https://pdbe.org/1otg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1otg RCSB], [https://www.ebi.ac.uk/pdbsum/1otg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1otg ProSAT]</span></td></tr>
 
</table>
===5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE===
== Function ==
 
[https://www.uniprot.org/uniprot/HPCD_ECOLX HPCD_ECOLX] Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET).
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_8547259}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 8547259 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ot/1otg_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_8547259}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1OTG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OTG OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1otg ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases., Subramanya HS, Roper DI, Dauter Z, Dodson EJ, Davies GJ, Wilson KS, Wigley DB, Biochemistry. 1996 Jan 23;35(3):792-802. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8547259 8547259]
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli C]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Dauter, Z.]]
[[Category: Dauter Z]]
[[Category: Davies, G J.]]
[[Category: Davies GJ]]
[[Category: Dodson, E J.]]
[[Category: Dodson EJ]]
[[Category: Roper, D I.]]
[[Category: Roper DI]]
[[Category: Subramanya, H S.]]
[[Category: Subramanya HS]]
[[Category: Wigley, D B.]]
[[Category: Wigley DB]]
[[Category: Wilson, K S.]]
[[Category: Wilson KS]]
[[Category: Hydroxymuconate]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:57:12 2008''
Retrieved from "https://proteopedia.org/1otg"