2or2: Difference between revisions

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{{Seed}}
[[Image:2or2.png|left|200px]]


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==Structure of the W47A/W242A Mutant of Bacterial Phosphatidylinositol-Specific Phospholipase C==
The line below this paragraph, containing "STRUCTURE_2or2", creates the "Structure Box" on the page.
<StructureSection load='2or2' size='340' side='right'caption='[[2or2]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2or2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OR2 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2or2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2or2 OCA], [https://pdbe.org/2or2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2or2 RCSB], [https://www.ebi.ac.uk/pdbsum/2or2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2or2 ProSAT]</span></td></tr>
{{STRUCTURE_2or2| PDB=2or2 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLC_BACTU PLC_BACTU] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/or/2or2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2or2 ConSurf].
<div style="clear:both"></div>


===Structure of the W47A/W242A Mutant of Bacterial Phosphatidylinositol-Specific Phospholipase C===
==See Also==
 
*[[Phospholipase C|Phospholipase C]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_17213187}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 17213187 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_17213187}}
 
==About this Structure==
2OR2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thuringiensis Bacillus thuringiensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OR2 OCA].
 
==Reference==
Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C., Shao C, Shi X, Wehbi H, Zambonelli C, Head JF, Seaton BA, Roberts MF, J Biol Chem. 2007 Mar 23;282(12):9228-35. Epub 2007 Jan 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17213187 17213187]
[[Category: Bacillus thuringiensis]]
[[Category: Bacillus thuringiensis]]
[[Category: Phosphatidylinositol diacylglycerol-lyase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Head JF]]
[[Category: Head, J F.]]
[[Category: Roberts MF]]
[[Category: Roberts, M F.]]
[[Category: Seaton BA]]
[[Category: Seaton, B A.]]
[[Category: Shao C]]
[[Category: Shao, C.]]
[[Category: Shi X]]
[[Category: Shi, X.]]
[[Category: Wehbi H]]
[[Category: Wehbi, H.]]
[[Category: Zambonelli C]]
[[Category: Zambonelli, C.]]
[[Category: Dimer]]
[[Category: Interfacially impaired]]
[[Category: Membrane binding]]
[[Category: Phosphatidylinositol-specific phospholipase c]]
[[Category: Pi-plc]]
[[Category: Tim barrel]]
 
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Retrieved from "https://proteopedia.org/2or2"