2guz: Difference between revisions

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{{Seed}}
[[Image:2guz.png|left|200px]]


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==Structure of the Tim14-Tim16 complex of the mitochondrial protein import motor==
The line below this paragraph, containing "STRUCTURE_2guz", creates the "Structure Box" on the page.
<StructureSection load='2guz' size='340' side='right'caption='[[2guz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2guz]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GUZ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
{{STRUCTURE_2guz|  PDB=2guz  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2guz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2guz OCA], [https://pdbe.org/2guz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2guz RCSB], [https://www.ebi.ac.uk/pdbsum/2guz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2guz ProSAT]</span></td></tr>
 
</table>
===Structure of the Tim14-Tim16 complex of the mitochondrial protein import motor===
== Function ==
 
[https://www.uniprot.org/uniprot/TIM14_YEAST TIM14_YEAST] Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1).<ref>PMID:14517234</ref> <ref>PMID:14638855</ref> <ref>PMID:14605210</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_16977310}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/2guz_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_16977310}}
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==About this Structure==
  </jmolCheckbox>
2GUZ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GUZ OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2guz ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Structure and function of Tim14 and Tim16, the J and J-like components of the mitochondrial protein import motor., Mokranjac D, Bourenkov G, Hell K, Neupert W, Groll M, EMBO J. 2006 Oct 4;25(19):4675-85. Epub 2006 Sep 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16977310 16977310]
<references/>
[[Category: Protein complex]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Bourenkov, G.]]
[[Category: Bourenkov G]]
[[Category: Groll, M.]]
[[Category: Groll M]]
[[Category: Hell, K.]]
[[Category: Hell K]]
[[Category: Mokranjac, D.]]
[[Category: Mokranjac D]]
[[Category: Neupert, W.]]
[[Category: Neupert W]]
[[Category: Dnaj-fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 03:19:37 2008''

Latest revision as of 09:30, 14 February 2024

Structure of the Tim14-Tim16 complex of the mitochondrial protein import motor

2guz, resolution 2.00Å

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