2lal: Difference between revisions

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{{Seed}}
[[Image:2lal.png|left|200px]]


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==CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT AT 2.3 ANGSTROMS RESOLUTION OF THE LENTIL LECTIN==
The line below this paragraph, containing "STRUCTURE_2lal", creates the "Structure Box" on the page.
<StructureSection load='2lal' size='340' side='right'caption='[[2lal]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2lal]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lens_culinaris Lens culinaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LAL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_2lal|  PDB=2lal  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lal OCA], [https://pdbe.org/2lal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lal RCSB], [https://www.ebi.ac.uk/pdbsum/2lal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lal ProSAT]</span></td></tr>
 
</table>
===CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT AT 2.3 ANGSTROMS RESOLUTION OF THE LENTIL LECTIN===
== Function ==
 
[https://www.uniprot.org/uniprot/LEC_LENCU LEC_LENCU] D-mannose specific lectin (By similarity).
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/la/2lal_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_8364026}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2LAL is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Lens_culinaris Lens culinaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAL OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2lal ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Crystal structure determination and refinement at 2.3-A resolution of the lentil lectin., Loris R, Steyaert J, Maes D, Lisgarten J, Pickersgill R, Wyns L, Biochemistry. 1993 Aug 31;32(34):8772-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8364026 8364026]
</StructureSection>
[[Category: Large Structures]]
[[Category: Lens culinaris]]
[[Category: Lens culinaris]]
[[Category: Protein complex]]
[[Category: Lisgarten J]]
[[Category: Lisgarten, J.]]
[[Category: Loris R]]
[[Category: Loris, R.]]
[[Category: Maes D]]
[[Category: Maes, D.]]
[[Category: Pickersgill R]]
[[Category: Pickersgill, R.]]
[[Category: Steyaert J]]
[[Category: Steyaert, J.]]
[[Category: Wyns L]]
[[Category: Wyns, L.]]
[[Category: Lectin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 05:51:57 2008''