1lqo: Difference between revisions
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New page: left|200px<br /><applet load="1lqo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lqo, resolution 2.00Å" /> '''Crystal Strutcure of... |
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== | ==Crystal Strutcure of the Fosfomycin Resistance Protein A (FosA) Containing Bound Thallium Cations== | ||
<StructureSection load='1lqo' size='340' side='right'caption='[[1lqo]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[1lqo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LQO FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lqo OCA], [https://pdbe.org/1lqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lqo RCSB], [https://www.ebi.ac.uk/pdbsum/1lqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lqo ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FOSA_PSEAE FOSA_PSEAE] Metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lq/1lqo_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lqo ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Armstrong RN]] | |||
[[Category: Armstrong | [[Category: Newcomer ME]] | ||
[[Category: Newcomer | [[Category: Pharris RE]] | ||
[[Category: Pharris | [[Category: Rife CL]] | ||
[[Category: Rife | |||
Latest revision as of 07:35, 14 February 2024
Crystal Strutcure of the Fosfomycin Resistance Protein A (FosA) Containing Bound Thallium Cations
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