1mui: Difference between revisions

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{{Seed}}
[[Image:1mui.png|left|200px]]


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==Crystal structure of HIV-1 protease complexed with Lopinavir.==
The line below this paragraph, containing "STRUCTURE_1mui", creates the "Structure Box" on the page.
<StructureSection load='1mui' size='340' side='right'caption='[[1mui]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mui]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MUI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene></td></tr>
{{STRUCTURE_1mui|  PDB=1mui  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mui OCA], [https://pdbe.org/1mui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mui RCSB], [https://www.ebi.ac.uk/pdbsum/1mui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mui ProSAT]</span></td></tr>
 
</table>
===Crystal structure of HIV-1 protease complexed with Lopinavir.===
== Function ==
 
[https://www.uniprot.org/uniprot/Q903J0_9HIV1 Q903J0_9HIV1]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12057670}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mu/1mui_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12057670}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1MUI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MUI OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mui ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
X-ray crystallographic structure of ABT-378 (lopinavir) bound to HIV-1 protease., Stoll V, Qin W, Stewart KD, Jakob C, Park C, Walter K, Simmer RL, Helfrich R, Bussiere D, Kao J, Kempf D, Sham HL, Norbeck DW, Bioorg Med Chem. 2002 Aug;10(8):2803-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12057670 12057670]
</StructureSection>
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bussiere, D.]]
[[Category: Bussiere D]]
[[Category: Helfrich, R.]]
[[Category: Helfrich R]]
[[Category: Jakob, C.]]
[[Category: Jakob C]]
[[Category: Kao, J.]]
[[Category: Kao J]]
[[Category: Kempf, D.]]
[[Category: Kempf D]]
[[Category: Norbeck, D W.]]
[[Category: Norbeck DW]]
[[Category: Park, C.]]
[[Category: Park C]]
[[Category: Qin, W.]]
[[Category: Qin W]]
[[Category: Sham, H L.]]
[[Category: Sham HL]]
[[Category: Simmer, R L.]]
[[Category: Simmer RL]]
[[Category: Stewart, K D.]]
[[Category: Stewart KD]]
[[Category: Stoll, V.]]
[[Category: Stoll V]]
[[Category: Walter, K.]]
[[Category: Walter K]]
[[Category: Hydrolase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:58:35 2008''
Retrieved from "https://proteopedia.org/1mui"