1lv3: Difference between revisions
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New page: left|200px<br /><applet load="1lv3" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lv3" /> '''Solution NMR Structure of Zinc Finger Protei... |
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== | ==Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.== | ||
<StructureSection load='1lv3' size='340' side='right'caption='[[1lv3]]' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[1lv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LV3 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lv3 OCA], [https://pdbe.org/1lv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lv3 RCSB], [https://www.ebi.ac.uk/pdbsum/1lv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lv3 ProSAT], [https://www.topsan.org/Proteins/NESGC/1lv3 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/YACG_ECOLI YACG_ECOLI] Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.<ref>PMID:18586829</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lv/1lv3_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lv3 ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Cort | [[Category: Cort JR]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Kennedy | [[Category: Kennedy MA]] | ||
[[Category: Ramelot TA]] | |||
[[Category: Ramelot | [[Category: Semesi A]] | ||
[[Category: Semesi | [[Category: Yee AA]] | ||
[[Category: Yee | |||
Latest revision as of 08:56, 9 May 2024
Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.
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