2o6f: Difference between revisions

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{{Seed}}
[[Image:2o6f.png|left|200px]]


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==Structure of metal- free rTp34 from Treponema pallidum==
The line below this paragraph, containing "STRUCTURE_2o6f", creates the "Structure Box" on the page.
<StructureSection load='2o6f' size='340' side='right'caption='[[2o6f]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2o6f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Treponema_pallidum Treponema pallidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O6F FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2o6f|  PDB=2o6f  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o6f OCA], [https://pdbe.org/2o6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o6f RCSB], [https://www.ebi.ac.uk/pdbsum/2o6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o6f ProSAT]</span></td></tr>
 
</table>
===Structure of metal- free rTp34 from Treponema pallidum===
== Function ==
 
[https://www.uniprot.org/uniprot/TA34_TREPA TA34_TREPA] This antigen is a pathogen-specific membrane immunogen.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_17192261}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 17192261 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o6/2o6f_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_17192261}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2O6F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Treponema_pallidum Treponema pallidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O6F OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o6f ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin., Deka RK, Brautigam CA, Tomson FL, Lumpkins SB, Tomchick DR, Machius M, Norgard MV, J Biol Chem. 2007 Feb 23;282(8):5944-58. Epub 2006 Dec 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17192261 17192261]
</StructureSection>
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Treponema pallidum]]
[[Category: Treponema pallidum]]
[[Category: Brautigam, C A.]]
[[Category: Brautigam CA]]
[[Category: Deka, R K.]]
[[Category: Deka RK]]
[[Category: Lumpkins, S B.]]
[[Category: Lumpkins SB]]
[[Category: Machius, M.]]
[[Category: Machius M]]
[[Category: Norgard, M V.]]
[[Category: Norgard MV]]
[[Category: Tomchick, D R.]]
[[Category: Tomchick DR]]
[[Category: Dimer]]
[[Category: Ig-fold]]
[[Category: Metal-ion binding]]
[[Category: Syphili]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:52:53 2008''
Retrieved from "https://proteopedia.org/2o6f"