1mwh: Difference between revisions

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{{Seed}}
[[Image:1mwh.png|left|200px]]


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==REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG==
The line below this paragraph, containing "STRUCTURE_1mwh", creates the "Structure Box" on the page.
<StructureSection load='1mwh' size='340' side='right'caption='[[1mwh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mwh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Reovirus_sp. Reovirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MWH FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTG:7-METHYL-GUANOSINE-5-TRIPHOSPHATE-5-GUANOSINE'>GTG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
{{STRUCTURE_1mwh|  PDB=1mwh  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mwh OCA], [https://pdbe.org/1mwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mwh RCSB], [https://www.ebi.ac.uk/pdbsum/1mwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mwh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RDRP_REOVD RDRP_REOVD] RNA-directed RNA polymerase that is involved in transcription and genome replication. Following infection, it catalyzes the synthesis of fully conservative plus strands. After core assembly, which consists in recruitment of one capped plus-strand for each genomic segments and polymerase complexes, the polymerase switches mode and catalyzes the synthesis of complementary minus-strands.


===REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG===
==See Also==
 
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12464184}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 12464184 is the PubMed ID number.
[[Category: Reovirus sp]]
-->
[[Category: Farsetta DL]]
{{ABSTRACT_PUBMED_12464184}}
[[Category: Harrison SC]]
 
[[Category: Nibert ML]]
==About this Structure==
[[Category: Tao Y]]
1MWH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Reovirus_sp. Reovirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MWH OCA].
 
==Reference==
RNA synthesis in a cage--structural studies of reovirus polymerase lambda3., Tao Y, Farsetta DL, Nibert ML, Harrison SC, Cell. 2002 Nov 27;111(5):733-45. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12464184 12464184]
[[Category: Reovirus sp.]]
[[Category: Single protein]]
[[Category: Farsetta, D L.]]
[[Category: Harrison, S C.]]
[[Category: Nibert, M L.]]
[[Category: Tao, Y.]]
[[Category: Polymerase]]
[[Category: Polymerase-cap analog complex]]
[[Category: Right hand configuration]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:14:28 2008''

Latest revision as of 07:49, 14 February 2024

REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG

1mwh, resolution 2.50Å

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