2jup: Difference between revisions

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{{Seed}}
[[Image:2jup.png|left|200px]]


<!--
==FBP28WW2 domain in complex with the PPLIPPPP peptide==
The line below this paragraph, containing "STRUCTURE_2jup", creates the "Structure Box" on the page.
<StructureSection load='2jup' size='340' side='right'caption='[[2jup]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2jup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JUP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jup OCA], [https://pdbe.org/2jup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jup RCSB], [https://www.ebi.ac.uk/pdbsum/2jup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jup ProSAT]</span></td></tr>
{{STRUCTURE_2jup|  PDB=2jup  |  SCENE=  }}
</table>
 
== Function ==
===FBP28WW2 domain in complex with the PPLIPPPP peptide===
[https://www.uniprot.org/uniprot/TCRG1_MOUSE TCRG1_MOUSE] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner (By similarity).
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_17915251}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 17915251 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/2jup_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_17915251}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jup ConSurf].
2JUP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JUP OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains., Ramirez-Espain X, Ruiz L, Martin-Malpartida P, Oschkinat H, Macias MJ, J Mol Biol. 2007 Nov 9;373(5):1255-68. Epub 2007 Aug 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17915251 17915251]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Synthetic construct]]
[[Category: Macias, M J.]]
[[Category: Macias MJ]]
[[Category: Martin-Malpartida, P.]]
[[Category: Martin-Malpartida P]]
[[Category: Oschkinat, H.]]
[[Category: Oschkinat H]]
[[Category: Ramirez-Espain, X.]]
[[Category: Ramirez-Espain X]]
[[Category: Ruiz, L.]]
[[Category: Ruiz L]]
[[Category: Actin-binding]]
[[Category: Alternative splicing]]
[[Category: Cell junction]]
[[Category: Coiled coil]]
[[Category: Cytoplasm]]
[[Category: Fbp28ww domain]]
[[Category: Membrane]]
[[Category: Nmr]]
[[Category: Nucleus]]
[[Category: Phosphorylation]]
[[Category: Polymorphism]]
[[Category: Pplipppp peptide]]
[[Category: Repressor]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 13:16:56 2008''
Retrieved from "https://proteopedia.org/2jup"