2i6w: Difference between revisions

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{{Seed}}
[[Image:2i6w.png|left|200px]]


<!--
==Crystal structure of the multidrug efflux transporter AcrB==
The line below this paragraph, containing "STRUCTURE_2i6w", creates the "Structure Box" on the page.
<StructureSection load='2i6w' size='340' side='right'caption='[[2i6w]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2i6w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I6W FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i6w OCA], [https://pdbe.org/2i6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i6w RCSB], [https://www.ebi.ac.uk/pdbsum/2i6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i6w ProSAT]</span></td></tr>
{{STRUCTURE_2i6w|  PDB=2i6w  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of the multidrug efflux transporter AcrB===
[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_17275331}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 17275331 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/2i6w_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_17275331}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i6w ConSurf].
2I6W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6W OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids., Das D, Xu QS, Lee JY, Ankoudinova I, Huang C, Lou Y, DeGiovanni A, Kim R, Kim SH, J Struct Biol. 2007 Jun;158(3):494-502. Epub 2006 Dec 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17275331 17275331]
__TOC__
[[Category: Escherichia coli]]
</StructureSection>
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Das, D.]]
[[Category: Das D]]
[[Category: Kim, S H.]]
[[Category: Kim SH]]
[[Category: Xu, Q S.]]
[[Category: Xu QS]]
[[Category: Acrb]]
[[Category: Membrane protein]]
[[Category: Multidrug efflux transporter]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:05:26 2008''

Latest revision as of 09:01, 21 February 2024

Crystal structure of the multidrug efflux transporter AcrB

2i6w, resolution 3.10Å

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