1mzr: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: left|200px<br /><applet load="1mzr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1mzr, resolution 2.13Å" /> '''Structure of dkga fr... |
No edit summary |
||
| (15 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== | ==Structure of dkga from E.coli at 2.13 A resolution solved by molecular replacement== | ||
<StructureSection load='1mzr' size='340' side='right'caption='[[1mzr]], [[Resolution|resolution]] 2.13Å' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[1mzr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MZR FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mzr OCA], [https://pdbe.org/1mzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mzr RCSB], [https://www.ebi.ac.uk/pdbsum/1mzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mzr ProSAT], [https://www.topsan.org/Proteins/BIGS/1mzr TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DKGA_ECOLI DKGA_ECOLI] Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mz/1mzr_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mzr ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Abergel | [[Category: Abergel C]] | ||
[[Category: Claverie | [[Category: Claverie JM]] | ||
[[Category: Jeudy S]] | |||
[[Category: Jeudy | [[Category: Monchois V]] | ||
[[Category: Monchois | |||
Latest revision as of 07:19, 25 October 2023
Structure of dkga from E.coli at 2.13 A resolution solved by molecular replacement
| ||||||||||||
