2d0a: Difference between revisions

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{{Seed}}
[[Image:2d0a.png|left|200px]]


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==Crystal structure of Bst-RNase HIII==
The line below this paragraph, containing "STRUCTURE_2d0a", creates the "Structure Box" on the page.
<StructureSection load='2d0a' size='340' side='right'caption='[[2d0a]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2d0a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D0A FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d0a OCA], [https://pdbe.org/2d0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d0a RCSB], [https://www.ebi.ac.uk/pdbsum/2d0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d0a ProSAT]</span></td></tr>
{{STRUCTURE_2d0a|  PDB=2d0a |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q6L6Q4_GEOSE Q6L6Q4_GEOSE] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.[HAMAP-Rule:MF_00053][SAAS:SAAS00088233]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d0/2d0a_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d0a ConSurf].
<div style="clear:both"></div>


===Crystal structure of Bst-RNase HIII===
==See Also==
 
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
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</StructureSection>
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{{ABSTRACT_PUBMED_16343535}}
 
==About this Structure==
2D0A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D0A OCA].
 
==Reference==
Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: a new type 2 RNase H with TBP-like substrate-binding domain at the N terminus., Chon H, Matsumura H, Koga Y, Takano K, Kanaya S, J Mol Biol. 2006 Feb 10;356(1):165-78. Epub 2005 Nov 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16343535 16343535]
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Ribonuclease H]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Chon H]]
[[Category: Chon, H.]]
[[Category: Kanaya S]]
[[Category: Kanaya, S.]]
[[Category: Koga Y]]
[[Category: Koga, Y.]]
[[Category: Matsumura H]]
[[Category: Matsumura, H.]]
[[Category: Takano K]]
[[Category: Takano, K.]]
[[Category: Ribonuclease h]]
[[Category: Rna/dna hybrid]]
 
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