2q9s: Difference between revisions

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{{Seed}}
[[Image:2q9s.png|left|200px]]


<!--
==Linoleic Acid Bound to Fatty Acid Binding Protein 4==
The line below this paragraph, containing "STRUCTURE_2q9s", creates the "Structure Box" on the page.
<StructureSection load='2q9s' size='340' side='right'caption='[[2q9s]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2q9s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q9S FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EIC:LINOLEIC+ACID'>EIC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2q9s|  PDB=2q9s |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q9s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q9s OCA], [https://pdbe.org/2q9s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q9s RCSB], [https://www.ebi.ac.uk/pdbsum/2q9s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q9s ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FABP4_MOUSE FABP4_MOUSE] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.<ref>PMID:12077340</ref> <ref>PMID:16574478</ref> <ref>PMID:17516629</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/2q9s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q9s ConSurf].
<div style="clear:both"></div>


===Linoleic Acid Bound to Fatty Acid Binding Protein 4===
==See Also==
 
*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
 
== References ==
<!--  
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_17761196}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 17761196 is the PubMed ID number.
</StructureSection>
-->
[[Category: Large Structures]]
{{ABSTRACT_PUBMED_17761196}}
 
==About this Structure==
2Q9S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q9S OCA].
 
==Reference==
Structural basis for activation of fatty acid-binding protein 4., Gillilan RE, Ayers SD, Noy N, J Mol Biol. 2007 Oct 5;372(5):1246-60. Epub 2007 Aug 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17761196 17761196]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Ayers SD]]
[[Category: Ayers, S D.]]
[[Category: Gillilan RE]]
[[Category: Gillilan, R E.]]
[[Category: Noy N]]
[[Category: Noy, N.]]
[[Category: Beta clamshell]]
[[Category: Lipid binding protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:21:49 2008''

Latest revision as of 09:14, 21 February 2024

Linoleic Acid Bound to Fatty Acid Binding Protein 4

2q9s, resolution 2.30Å

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