1s8a: Difference between revisions

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{{Seed}}
[[Image:1s8a.png|left|200px]]


<!--
==H98Q Mutant of Methylglyoxal Synthase from E. coli complexed with Phosphoglycolic Acid==
The line below this paragraph, containing "STRUCTURE_1s8a", creates the "Structure Box" on the page.
<StructureSection load='1s8a' size='340' side='right'caption='[[1s8a]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1s8a]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S8A FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene></td></tr>
{{STRUCTURE_1s8a|  PDB=1s8a  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s8a OCA], [https://pdbe.org/1s8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s8a RCSB], [https://www.ebi.ac.uk/pdbsum/1s8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s8a ProSAT]</span></td></tr>
 
</table>
===H98Q Mutant of Methylglyoxal Synthase from E. coli complexed with Phosphoglycolic Acid===
== Function ==
 
[https://www.uniprot.org/uniprot/MGSA_ECOLI MGSA_ECOLI]
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_15049687}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 15049687 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s8/1s8a_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_15049687}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1S8A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S8A OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s8a ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
Mutagenic studies on histidine 98 of methylglyoxal synthase: effects on mechanism and conformational change., Marks GT, Susler M, Harrison DH, Biochemistry. 2004 Apr 6;43(13):3802-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15049687 15049687]
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Methylglyoxal synthase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Harrison DH]]
[[Category: Harrison, D H.]]
[[Category: Marks GT]]
[[Category: Marks, G T.]]
[[Category: Susler M]]
[[Category: Susler, M.]]
[[Category: Glycolytic bypass]]
[[Category: Lyase]]
[[Category: Methylglyoxal]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:42:56 2008''
Retrieved from "https://proteopedia.org/1s8a"