1nl7: Difference between revisions

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New page: left|200px<br /><applet load="1nl7" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nl7, resolution 1.903Å" /> '''Z. ramigera biosynt...
 
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[[Image:1nl7.jpg|left|200px]]<br /><applet load="1nl7" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1nl7, resolution 1.903&Aring;" />
'''Z. ramigera biosynthetic thiolase, acetylated enzyme complexed with CoA at pH 9.5'''<br />


==About this Structure==
==Z. ramigera biosynthetic thiolase, acetylated enzyme complexed with CoA at pH 9.5==
1NL7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Zoogloea_ramigera Zoogloea ramigera] with SO4 and COA as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NL7 OCA].  
<StructureSection load='1nl7' size='340' side='right'caption='[[1nl7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
[[Category: Acetyl-CoA C-acetyltransferase]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1nl7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Zoogloea_ramigera Zoogloea ramigera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NL7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NL7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.903&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=SCY:S-ACETYL-CYSTEINE'>SCY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nl7 OCA], [https://pdbe.org/1nl7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nl7 RCSB], [https://www.ebi.ac.uk/pdbsum/1nl7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nl7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THIL_SHIZO THIL_SHIZO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nl/1nl7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nl7 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Thiolase 3D structures|Thiolase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Zoogloea ramigera]]
[[Category: Zoogloea ramigera]]
[[Category: Kursula, P.]]
[[Category: Kursula P]]
[[Category: Wierenga, R.K.]]
[[Category: Wierenga RK]]
[[Category: COA]]
[[Category: SO4]]
[[Category: acetylation]]
[[Category: enzyme-substrate complex]]
[[Category: thiolase fold]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 22:21:40 2007''