1n23: Difference between revisions

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{{Seed}}
[[Image:1n23.png|left|200px]]


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==(+)-Bornyl diphosphate synthase: Complex with Mg, pyrophosphate, and (1R,4S)-2-azabornane==
The line below this paragraph, containing "STRUCTURE_1n23", creates the "Structure Box" on the page.
<StructureSection load='1n23' size='340' side='right'caption='[[1n23]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1n23]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salvia_officinalis Salvia officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N23 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2BN:(1R,4S)-2-AZABORNANE'>2BN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
{{STRUCTURE_1n23|  PDB=1n23  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n23 OCA], [https://pdbe.org/1n23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n23 RCSB], [https://www.ebi.ac.uk/pdbsum/1n23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n23 ProSAT]</span></td></tr>
 
</table>
===(+)-Bornyl diphosphate synthase: Complex with Mg, pyrophosphate, and (1R,4S)-2-azabornane===
== Function ==
 
[https://www.uniprot.org/uniprot/BPPS_SALOF BPPS_SALOF] Catalyzes the formation of the (+)-camphor precursor (+)-bornyl diphosphate from geranyl diphosphate. The enzyme also produces significant amounts of (+)-alpha-pinene, (+)-camphene, and (+-)-limonene.<ref>PMID:9614092</ref>
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12432096}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/1n23_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12432096}}
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1N23 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salvia_officinalis Salvia officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N23 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n23 ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclase., Whittington DA, Wise ML, Urbansky M, Coates RM, Croteau RB, Christianson DW, Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15375-80. Epub 2002 Nov 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12432096 12432096]
<references/>
[[Category: Geranyl-diphosphate cyclase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salvia officinalis]]
[[Category: Salvia officinalis]]
[[Category: Single protein]]
[[Category: Christianson DW]]
[[Category: Christianson, D W.]]
[[Category: Coates RM]]
[[Category: Coates, R M.]]
[[Category: Croteau RB]]
[[Category: Croteau, R B.]]
[[Category: Urbansky M]]
[[Category: Urbansky, M.]]
[[Category: Whittington DA]]
[[Category: Whittington, D A.]]
[[Category: Wise ML]]
[[Category: Wise, M L.]]
[[Category: Terpene synthase fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:48:31 2008''

Latest revision as of 07:51, 14 February 2024

(+)-Bornyl diphosphate synthase: Complex with Mg, pyrophosphate, and (1R,4S)-2-azabornane

1n23, resolution 2.40Å

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