3c4d: Difference between revisions

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m Protected "3c4d" [edit=sysop:move=sysop]
 
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{{Seed}}
#REDIRECT [[4fk3]] This PDB entry is obsolete and replaced by 4fk3
[[Image:3c4d.png|left|200px]]
 
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{{STRUCTURE_3c4d|  PDB=3c4d  |  SCENE=  }}
 
===B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203===
 
 
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{{ABSTRACT_PUBMED_18287029}}
 
==About this Structure==
3C4D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C4D OCA].
 
==Reference==
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity., Tsai J, Lee JT, Wang W, Zhang J, Cho H, Mamo S, Bremer R, Gillette S, Kong J, Haass NK, Sproesser K, Li L, Smalley KS, Fong D, Zhu YL, Marimuthu A, Nguyen H, Lam B, Liu J, Cheung I, Rice J, Suzuki Y, Luu C, Settachatgul C, Shellooe R, Cantwell J, Kim SH, Schlessinger J, Zhang KY, West BL, Powell B, Habets G, Zhang C, Ibrahim PN, Hirth P, Artis DR, Herlyn M, Bollag G, Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3041-6. Epub 2008 Feb 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18287029 18287029]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Single protein]]
[[Category: Wang, W.]]
[[Category: Zhang, K Y.J.]]
[[Category: Atp-binding]]
[[Category: B-raf]]
[[Category: Braf]]
[[Category: Cardiomyopathy]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Metal-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phorbol-ester binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Proto-oncogene]]
[[Category: Raf]]
[[Category: Serine/threonine kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: V600e]]
[[Category: Zinc]]
[[Category: Zinc-finger]]
 
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Latest revision as of 05:13, 8 August 2012

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