1ny4: Difference between revisions
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New page: left|200px<br /><applet load="1ny4" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ny4" /> '''Solution structure of the 30S ribosomal prot... |
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== | ==Solution structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii. Northeast Structural Genomics Consortium target JR19.== | ||
We report NMR assignments and solution structure of the 71-residue 30S | <StructureSection load='1ny4' size='340' side='right'caption='[[1ny4]]' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1ny4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NY4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ny4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ny4 OCA], [https://pdbe.org/1ny4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ny4 RCSB], [https://www.ebi.ac.uk/pdbsum/1ny4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ny4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RS28_PYRHO RS28_PYRHO] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/1ny4_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ny4 ConSurf]. | |||
<div style="clear:both"></div> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
We report NMR assignments and solution structure of the 71-residue 30S ribosomal protein S28E from the archaean Pyrococcus horikoshii, target JR19 of the Northeast Structural Genomics Consortium. The structure, determined rapidly with the aid of automated backbone resonance assignment (AutoAssign) and automated structure determination (AutoStructure) software, is characterized by a four-stranded beta-sheet with a classic Greek-key topology and an oligonucleotide/oligosaccharide beta-barrel (OB) fold. The electrostatic surface of S28E exhibits positive and negative patches on opposite sides, the former constituting a putative binding site for RNA. The 13 C-terminal residues of the protein contain a consensus sequence motif constituting the signature of the S28E protein family. Surprisingly, this C-terminal segment is unstructured in solution. | |||
Solution NMR structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii.,Aramini JM, Huang YJ, Cort JR, Goldsmith-Fischman S, Xiao R, Shih LY, Ho CK, Liu J, Rost B, Honig B, Kennedy MA, Acton TB, Montelione GT Protein Sci. 2003 Dec;12(12):2823-30. PMID:14627742<ref>PMID:14627742</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 1ny4" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Ribosomal protein S28|Ribosomal protein S28]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pyrococcus horikoshii]] | [[Category: Pyrococcus horikoshii]] | ||
[[Category: Acton TB]] | |||
[[Category: Acton | [[Category: Aramini JM]] | ||
[[Category: Aramini | [[Category: Cort JR]] | ||
[[Category: Cort | [[Category: Ho CK]] | ||
[[Category: Ho | [[Category: Huang YJ]] | ||
[[Category: Huang | [[Category: Kennedy MA]] | ||
[[Category: Kennedy | [[Category: Montelione GT]] | ||
[[Category: Montelione | [[Category: Shih L-Y]] | ||
[[Category: Xiao R]] | |||
[[Category: Shih | |||
[[Category: Xiao | |||
Latest revision as of 08:55, 22 May 2024
Solution structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii. Northeast Structural Genomics Consortium target JR19.
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